Tag: protein

Bence Jones Protein – What is it?

The Bence-Jones protein (BJP) was described in 1962 as “free monoclonal light chains”, synthesized by a single clone of B cells. Normal plasma cells appear to produce a slight excess of light chains, but B cell neoplasms may produce a much greater excess. Once the mechanism of tubular reabsorption becomes saturated, BJPs are excreted in …